Systems, methods, and computer programs are disclosed for managing memory channel connectivity. One embodiment of a system comprises a high-bandwidth memory client, a low-bandwidth memory client, and an address translator. The high-bandwidth memory client is electrically coupled to each of a plurality of memory channels via an interconnect. The low-bandwidth memory client is electrically coupled to only a portion of the plurality of memory channels via the interconnect. The address translator is in communication with the high-bandwidth memory client and configured to perform physical address manipulation when a memory page to be accessed by the high-bandwidth memory client is shared with the low-bandwidth memory client.