Disclosed are various examples for dynamically generating configuration profiles based on an operating system of a device. A computing environment can determine that a configuration profile configured for a type of the client device has not been created. If so, the computing environment can identify an operating system of the client device, determine a format for the configuration profile based on the operating system, and generating a configuration profile in accordance with the format and the operating system. The configuration profile can include a value for a setting previously defined that is common to a plurality of different operating systems.