A method for configuring a neural network comprises: accessing a plurality of three-dimensional (3D) emission image data sets collected by an emission scanner from respective brains of respective subjects; transforming each of the plurality of 3D emission image data sets to a respective two-dimensional (2D) image; cropping portions of each respective 2D image to remove image data corresponding to tissue outside of a striatum of each of the respective brains, to form respective cropped 2D striatum images; and training a neural network to detect a presence of a Parkinsonian syndrome using the cropped 2D striatum images.