Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing load reduction optimization. In one aspect, a method includes accessing load reduction parameters for a load reduction event, accessing energy consumption models for multiple systems involved in the load reduction event, and performing, based on the load reduction parameters and the energy consumption models, a plurality of simulations of load reduction events that simulate variations in control parameters used to control the multiple systems. The method also includes optimizing, against a load reduction curve, the load reduction event by iteratively modifying the control parameters used in the plurality of simulations of load reduction events, and outputting the optimal load reduction event with optimized control parameters.