Invention Grant
- Patent Title: Antiviral vaccines with improved cellular immunogenicity
-
Application No.: US16441703Application Date: 2019-06-14
-
Publication No.: US10772952B2Publication Date: 2020-09-15
- Inventor: Dan H. Barouch , Bette T. Korber , William M. Fischer
- Applicant: Beth Israel Deaconess Medical Center, Inc. , Triad National Security, LLC
- Applicant Address: US MA Boston US NM Los Alamos
- Assignee: Beth Israel Deaconess Medical Center, Inc.,Triad National Security, LLC
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.,Triad National Security, LLC
- Current Assignee Address: US MA Boston US NM Los Alamos
- Agency: Ice Miller LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; C12N7/00 ; C07K14/005 ; C07K14/025 ; A61K39/21 ; A61K39/235 ; A61K39/275
Abstract:
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.
Public/Granted literature
- US20190314492A1 ANTIVIRAL VACCINES WITH IMPROVED CELLULAR IMMUNOGENICITY Public/Granted day:2019-10-17
Information query
