Mechanical circulatory assist systems and related methods accommodate the connection of a second patient interface module used to control a circulatory assist pump without having to disconnect a first patient interface module used to control the circulatory assist pump. A mechanical circulatory assist system includes a blood pump, a first patient interface module, and a first connector. The first patient interface module is operatively coupled with the blood pump and configured to control operation of the blood pump. The first connector is operatively coupled with the blood pump and configured to couple with a second patient interface module configured to control operation of the blood pump without decoupling of the first interface module from the blood pump.