Invention Grant
- Patent Title: IgG bispecific antibodies and processes for preparation
-
Application No.: US15545047Application Date: 2016-01-21
-
Publication No.: US10774156B2Publication Date: 2020-09-15
- Inventor: Hector Aldaz , Shane Krummen Atwell , Stephen John Demarest , Karen Jean Froning , Brian Arthur Kuhlman , Andrew Philip Leaver-Fay
- Applicant: Eli Lilly and Company , The University of North Carolina at Chapel Hill
- Applicant Address: US IN Indianapolis US NC Chapel Hill
- Assignee: Eli Lilly and Company,The University of North Carolina at Chapel Hill
- Current Assignee: Eli Lilly and Company,The University of North Carolina at Chapel Hill
- Current Assignee Address: US IN Indianapolis US NC Chapel Hill
- Agent Robert L Sharp
- International Application: PCT/US2016/014313 WO 20160121
- International Announcement: WO2016/118742 WO 20160728
- Main IPC: C07K16/40
- IPC: C07K16/40 ; C07K16/00 ; C07K16/30 ; C07K16/46 ; C07K16/32 ; C07K16/28
Abstract:
The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
Public/Granted literature
- US20180009908A1 IgG Bispecific Antibodies and Processes for Preparation Public/Granted day:2018-01-11
Information query
