Invention Grant
- Patent Title: Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
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Application No.: US15309986Application Date: 2015-05-19
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Publication No.: US10774387B2Publication Date: 2020-09-15
- Inventor: Jun Luo , Emmanuel S. Antaonarakis , Changxue Lu
- Applicant: The Johns Hopkins University
- Applicant Address: US MD Baltimore
- Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee: THE JOHNS HOPKINS UNIVERSITY
- Current Assignee Address: US MD Baltimore
- Agency: Ballard Spahr LLP
- International Application: PCT/US2015/031584 WO 20150519
- International Announcement: WO2015/179404 WO 20151126
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6886

Abstract:
Methods of the present disclosure provide for detection of mutations and splice variants of the androgen receptor using a non-invasive approach, RNAseq, for examining circulating tumor cells.
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