An interferometric measurement system measures a spun optical fiber sensor that includes multiple optical cores configured in the fiber sensor. A calibration machine includes a calibration fixture having known dimensions, one or more automatically controllable actuators for wrapping the fiber sensor starting at one end of the fiber sensor onto a calibration fixture having known dimensions, and an actuator controller configured to control the one or more actuators with actuator control signals. Interferometric detection circuitry, coupled to the actuator controller and to the other end of the fiber sensor, detects measured interferometric pattern data associated with each of the multiple cores when the fiber sensor is wrapped onto the calibration fixture. Data processing circuitry determines compensation parameters that compensate for variations between an optimal configuration of the multiple cores and an actual configuration of the multiple cores in the fiber sensor based on the detected measured interferometric pattern data. The compensation parameters compensate subsequently-obtained measurement interferometric pattern data for the fiber sensor.