Technologies for framework-level audio device virtualization include a computing device that executes multiple application framework instances. The computing device monitors for an application framework instance switch and, in response to an application framework instance switch, determines whether the current application framework instance is in the foreground. If in the foreground, the computing device selects a physical audio output device. The computing device may output audio data associated with the current application framework instance using a kernel audio driver associated with the physical audio output device. If not in the foreground, the computing device selects a null audio output device using a null audio hardware abstraction layer (HAL). The null audio HAL may sleep for the duration of audio data associated with the current application framework instance. The null audio HAL may be an operating-system- and device-independent shared library of the computing device. Other embodiments are described and claimed.