A device comprises a 3D array of cells arranged for execution of a sum-of-products operation, the cells in the 3D array disposed in cross-points of a plurality of vertical lines and a plurality of horizontal lines, the cells having programmable conductances. A gate driver is coupled to gate lines which applies control gate voltages which in combination with the programmable conductances of the cells correspond to weights Wxyz of terms in the sum-of-products operation. An input driver applies voltages to cells in the array corresponding to input variables Xy. A sensing circuit senses a sum of currents from cells in the 3D array corresponding to the sum-of-products.