The invention relates to deployable magnetic compression devices and systems and methods for the deployment of such magnetic compression devices. The magnetic compression devices are particularly useful for creating anastomoses, e.g., in the gastrointestinal tract. The devices are especially useful for minimally-invasive delivery, e.g., using endoscopic techniques. The systems, devices, and methods can be used to treat a variety of gastrointestinal and metabolic diseases, such as diabetes, obesity, and cancer.