Invention Grant
- Patent Title: Vector co-expressing vaccine and costimulatory molecules
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Application No.: US16016770Application Date: 2018-06-25
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Publication No.: US10780161B2Publication Date: 2020-09-22
- Inventor: Taylor Schreiber , George Fromm
- Applicant: Heat Biologics, Inc.
- Applicant Address: US NC Durham
- Assignee: Heat Biologics, Inc.
- Current Assignee: Heat Biologics, Inc.
- Current Assignee Address: US NC Durham
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K14/705 ; C12N15/86 ; C12N15/10 ; C12N15/13 ; C12N15/62 ; C12N15/85 ; A61K39/39 ; A61K39/42 ; A61K48/00 ; C07K16/28 ; A61K39/00 ; A61K39/395
Abstract:
Compositions and methods for co-expressing a secretable vaccine protein (such as gp96-Ig) and T-cell co-stimulatory molecules from a single vector, among others, are provided herein. Materials and methods for using gp96-Ig vaccination and T-cell co-stimulation to treat a clinical condition (e.g., cancer) in a subject also are provided.
Public/Granted literature
- US20180360955A1 VECTOR CO-EXPRESSING VACCINE AND COSTIMULATORY MOLECULES Public/Granted day:2018-12-20
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