Invention Grant
![N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[C]pyrrole negative allosteric modulators of NR2B](/docs/US/2020-09-22/US10781174B2/abs.jpg.600x600.jpg)
- Patent Title: N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[C]pyrrole negative allosteric modulators of NR2B
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Application No.: US16255500Application Date: 2019-01-23
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Publication No.: US10781174B2Publication Date: 2020-09-22
- Inventor: David R. Anderson , Robert A. Volkmann , Frank S. Menniti
- Applicant: CADENT THERAPEUTICS, INC.
- Applicant Address: US MA Cambridge
- Assignee: CADENT THERAPEUTICS, INC.
- Current Assignee: CADENT THERAPEUTICS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Brinks Gilson & Lione
- Agent Yuezhong Feng
- Main IPC: A61K31/403
- IPC: A61K31/403 ; A61P25/00 ; C07D209/52 ; C07D403/12 ; C07D401/14 ; C07D401/06 ; C07D401/12 ; C07D403/06 ; A61P25/28 ; A61P25/22 ; A61P25/24 ; A61P25/16
![N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[C]pyrrole negative allosteric modulators of NR2B](/abs-image/US/2020/09/22/US10781174B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure relates to N-alkylaryl-5-oxyaryl-octadihydrocyclopent[c]pyrrole negative allosteric modulators of NR2B receptors useful in the treatment of neurological diseases having the Formula I: where R1, R2, L1, L2, X, Y, and Y′ are described therein.
Public/Granted literature
- US20190152912A1 N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B Public/Granted day:2019-05-23
Information query
