Invention Grant
![5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors](/docs/US/2020-09-22/US10781208B2/abs.jpg.600x600.jpg)
- Patent Title: 5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors
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Application No.: US16347630Application Date: 2017-11-17
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Publication No.: US10781208B2Publication Date: 2020-09-22
- Inventor: Jianyong Chen , Liu Liu , Xuyuan Dong , Chao-Yie Yang , Donna McEachern , Shaomeng Wang
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2017/621440 WO 20171117
- International Announcement: WO2018/094134 WO 20180524
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00
![5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors](/abs-image/US/2020/09/22/US10781208B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure provides compounds represented by Formula (I), and the pharmaceutically acceptable salts and solvates thereof wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer. and ®
Public/Granted literature
- US20190315741A1 5,6-DIHYDRO-11H-INDOLO[2,3-B]QUINOLIN-11-ONES AS ALK INHIBITORS Public/Granted day:2019-10-17
Information query
