Invention Grant
- Patent Title: α1-antitrypsin compositions and methods of treating autoimmune diseases
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Application No.: US16166990Application Date: 2018-10-22
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Publication No.: US10781248B2Publication Date: 2020-09-22
- Inventor: Terry B. Strom , Maria Koulmanda
- Applicant: Beth Israel Deaconess Medical Center, Inc.
- Applicant Address: US MA Boston
- Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: C07K14/81
- IPC: C07K14/81 ; C12N15/62 ; A61K47/68

Abstract:
The specification provides compositions comprising chimeric proteins comprising AAT conjugated to an Fc region of an immunoglobulin. Methods for treating autoimmune disease, e.g., diabetes, e.g., Type 1 and Type 2 diabetes, are also provided.
Public/Granted literature
- US20190276516A1 ALPHA1 -ANTITRYPSIN COMPOSITIONS AND METHODS OF TREATING AUTOIMMUNE DISEASES Public/Granted day:2019-09-12
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