Invention Grant
- Patent Title: NMR multi-dimensional method for measuring coupling constants within several coupling networks
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Application No.: US16315084Application Date: 2018-01-08
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Publication No.: US10782255B2Publication Date: 2020-09-22
- Inventor: Yanqin Lin , Qing Zeng , Jinyong Chen , Zhong Chen
- Applicant: XIAMEN UNIVERSITY
- Applicant Address: CN Xiamen
- Assignee: XIAMEN UNIVERSITY
- Current Assignee: XIAMEN UNIVERSITY
- Current Assignee Address: CN Xiamen
- Agency: Cooper Legal Group, LLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2300f8fc
- International Application: PCT/CN2018/071808 WO 20180108
- International Announcement: WO2018/130132 WO 20180719
- Main IPC: G01V3/00
- IPC: G01V3/00 ; G01N24/08 ; G01R33/46

Abstract:
This invention provides a NMR multi-dimensional method for measuring coupling constants within several coupling networks. At first, a 90° hard pulse was performed to flip the magnetization from the Z axis to the XY plane. After t1/2, a selective 180° pulse is implemented with a simultaneous Z-direction gradient, thus reversing different protons at different slices. Then the PSYCHE element is implemented. After another t1/2, the gradient G1 and Gp are implemented. At last, the EPSI readout is used to simultaneously record both the chemical-shift and the spatial information. As a result, from different specific slices, we can extract the scalar couplings between the proton reversed at this slice and other protons. These couplings lead to splittings in the indirect dimension, from which relevant coupling constants can be measured.
Public/Granted literature
- US20190310210A1 An NMR multi-dimensional method for measuring coupling constants within several coupling networks Public/Granted day:2019-10-10
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