An apparatus comprises processing circuitry (4) and an instruction decoder (6) which supports vector instructions for which multiple lanes of processing are performed on respective data elements of a vector value. In response to a vector predication instruction, the instruction decoder (6) controls the processing circuitry (4) to set control information based on the outcome of a number of element comparison operations each for determining whether a corresponding element passes or fails a test condition. The control information controls processing of a predetermined number of subsequent vector instructions after the vector predication instruction. The predetermined number is hard-wired or identified by the vector predication instruction. For one of the subsequent vector instructions, an operation for a given portion of a given lane of vector processing is masked based on the outcome indicated by the control information for a corresponding data element.