Embodiments of the disclosure provide systems and methods for segmenting a medical image. An exemplary system includes a communication interface configured to receive the medical image acquired by an image acquisition device. The system further includes a memory configured to store a multi-level learning network including at least a first convolution block and a second convolution block. The second convolution block has at least one convolution layer. The system also includes a processor. The processor is configured to determine a first feature map by applying the first convolution block to the medical image, and determine a second feature map by applying the second convolution block to the first feature map. The processor is further configured to determine a first level feature map by concatenating the first feature map and the second feature map. The processor is also configured to obtain a first level segmented image based on the first level feature map.