Invention Grant
- Patent Title: Two stage cellularization strategy for the fabrication of bioartificial hearts
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Application No.: US15725812Application Date: 2017-10-05
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Publication No.: US10792145B2Publication Date: 2020-10-06
- Inventor: Ravi K. Birla
- Applicant: Ravi K. Birla
- Applicant Address: US TX Houston
- Assignee: UNIVERSITY OF HOUSTON SYSTEM
- Current Assignee: UNIVERSITY OF HOUSTON SYSTEM
- Current Assignee Address: US TX Houston
- Agency: Winstead PC
- Main IPC: A61F2/08
- IPC: A61F2/08 ; A61M1/12 ; C12N5/077 ; A61L27/22 ; A61L27/34 ; A61L27/36 ; A61L27/38

Abstract:
In some embodiments, the present disclosure pertains to a method of fabricating an artificial heart muscle (AHM) patch. In some embodiments, the method includes obtaining and/or isolating cells from a subject. In some embodiments, the cells are primary cardiac cells. In some embodiments, the method further includes forming a scaffold. In some embodiments, the method includes seeding the cells in the fibrin gel scaffold. In some embodiments, the method includes culturing the cells seeded in the fibrin gel scaffold under conditions appropriate for the formation of an artificial heart muscle (AHM) patch.
Public/Granted literature
- US20180042714A1 TWO STAGE CELLULARIZATION STRATEGY FOR THE FABRICATION OF BIOARTIFICIAL HEARTS Public/Granted day:2018-02-15
Information query
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