Invention Grant
- Patent Title: Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent
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Application No.: US15034437Application Date: 2014-11-07
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Publication No.: US10792248B2Publication Date: 2020-10-06
- Inventor: Takahiro Tada , Kazuhiro Kagami , Shiro Yokota , Kenta Kikuchi
- Applicant: ACTIVUS PHARMA CO., LTD.
- Applicant Address: JP Funabashi-Shi
- Assignee: ACTIVUS PHARMA CO., LTD.
- Current Assignee: ACTIVUS PHARMA CO., LTD.
- Current Assignee Address: JP Funabashi-Shi
- Agency: Cowan, Liebowitz & Latman, P.C.
- Agent Mark Montague
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7280f41e
- International Application: PCT/JP2014/005603 WO 20141107
- International Announcement: WO2015/068397 WO 20150514
- Main IPC: A61K9/10
- IPC: A61K9/10 ; A61K47/32 ; A61K47/38 ; A61K31/7048 ; A61K9/00 ; A61K9/14 ; A61K47/10 ; A61K47/26 ; A61K31/7052 ; A61K47/44

Abstract:
An aqueous suspension preparation that comprises a macrolide antibacterial agent as an active component.The aqueous suspension preparation is characterized by comprising nanoparticles of a macrolide antibacterial agent and a dispersion stabilizer; an aqueous suspension in which the average particle size of nanoparticles is 500 nm or less and the D90 particle size is 1,500 nm or less; a parenterally administered pharmaceutical composition that comprises this aqueous suspension preparation; an injection preparation; and eye drops or ear drops, more specifically, eye drops for the treatment or prevention of inflammatory diseases of the eye or ear drops for the treatment or prevention of inflammatory diseases of the ear.
Public/Granted literature
- US20160271057A1 AQUEOUS SUSPENSION PREPARATION COMPRISING NANOPARTICLES OF MACROLIDE ANTIBACTERIAL AGENT Public/Granted day:2016-09-22
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