Invention Grant
- Patent Title: Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
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Application No.: US16740861Application Date: 2020-01-13
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Publication No.: US10792360B1Publication Date: 2020-10-06
- Inventor: Thomas Schall , James J. Campbell
- Applicant: ChemoCentryx, Inc.
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Barnes & Thornburg LLP
- Agent Ryan L. Marshall; Jonathan M. Hartley
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K31/44 ; A61K39/395 ; C07K16/28 ; A61P1/00 ; A61K39/00
Abstract:
Provided herein are compositions, methods and kits for treating inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with IBD a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (CCR9) inhibitor compound and a therapeutically effective amount of an anti-TNFα antibody. Also provided herein is a kit containing the CCR9 inhibitor compound and anti-TNFα antibody.
Information query
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