The invention relates to a needleless injection device or a device for the needleless injection of a substance into a tissue or body, with which device a substance, in particular an active substance, can be injected by means of high pressure. A device according to the invention comprises a chamber (11) containing a pyrotechnic material, wherein the chamber has a fixed double membrane (13, 15) at a discharge opening, wherein the skin-side membrane (15) of the double membrane (13, 15) is provided with a substance application (25).A successful injection lies in the fact that sufficient substance is introduced into the body through the tissue barrier or body barrier, in particular such as the skin.