Invention Grant
- Patent Title: Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors
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Application No.: US15878694Application Date: 2018-01-24
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Publication No.: US10793538B2Publication Date: 2020-10-06
- Inventor: Edward Holson , Fanny Lazzaro , David Olson , Florence Fevrier Wagner , Michel Weiwer
- Applicant: The Broad Institute, Inc.
- Applicant Address: US MA Cambridge
- Assignee: The Broad Institute, Inc.
- Current Assignee: The Broad Institute, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07D309/28
- IPC: C07D309/28 ; C07C259/08 ; C07C323/61 ; C07D209/08 ; C07D211/78 ; C07D211/96 ; C07D263/16
Abstract:
The present invention provides compounds of formula (I): or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Ra are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.
Public/Granted literature
- US20180215726A1 CYCLOALKENYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS Public/Granted day:2018-08-02
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