Invention Grant
- Patent Title: Method for producing antigen-specific B cells and their use for the production of hybridoma cells and monoclonal antibodies
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Application No.: US15486360Application Date: 2017-04-13
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Publication No.: US10793620B2Publication Date: 2020-10-06
- Inventor: Detlef Schmechel
- Applicant: BioGenes GmbH
- Applicant Address: DE Berlin
- Assignee: BIOGENES GMBH
- Current Assignee: BIOGENES GMBH
- Current Assignee Address: DE Berlin
- Agency: Fox Rothschild, LLP
- Agent Gregory A. Nelson; Amy A. Dobbelaere
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7723b8fa
- Main IPC: C12N5/12
- IPC: C12N5/12 ; C07K16/00 ; C12N5/0781 ; A01K67/027 ; C12N5/16 ; A61K39/00

Abstract:
The invention refers to a non-therapeutic method for producing antigen-specific B cells by using the adoptive cell transfer of primed B cells, especially of spleen cells including B cells of a previously immunized non-human animal and by administering an antigen of interest to a naïve non-human animal.
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