Invention Grant
- Patent Title: Adrenomedullin binder for use in therapy of cancer
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Application No.: US15105712Application Date: 2014-12-19
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Publication No.: US10793626B2Publication Date: 2020-10-06
- Inventor: Andreas Bergmann
- Applicant: ANGIOBIOMED GMBH
- Applicant Address: DE Hennigsdorf
- Assignee: ANGIOBIOMED GMBH
- Current Assignee: ANGIOBIOMED GMBH
- Current Assignee Address: DE Hennigsdorf
- Agency: Millen, White, Zelano & Branigan, PC
- Agent Ryan Pool
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7fcc3c22
- International Application: PCT/EP2014/078870 WO 20141219
- International Announcement: WO2015/092021 WO 20150625
- Main IPC: C07K16/22
- IPC: C07K16/22 ; C07K16/26 ; A61K39/395 ; A61K9/00 ; A61K45/06 ; C07K16/30 ; A61K39/00
Abstract:
Subject matter of the present invention is an anti-ADM antibody or anti-ADM antibody fragment or anti-ADM non-Ig scaffold binding to the C-terminal portion of ADM, the aa 43-52 of ADM (SEQ ID NO: 1): APRSKISPQGY-NH2 for use in a therapy of cancer. Subject matter of the present invention is anti-ADM antibody or anti-ADM antibody fragment or anti-ADM non-Ig scaffold for use in the treatment of cancer according to claim 1 wherein said anti-ADM antibody or anti-ADM antibody fragment or anti-ADM non-Ig scaffold requires the presence of a C-terminally amidated tyrosine residue within the C-terminal portion of ADM, the aa 43-52 of ADM (SEQ ID NO: 1): APRSKISPQGY-NH2, for binding.
Public/Granted literature
- US20160319007A1 ADRENOMEDULLIN BINDER FOR USE IN THERAPY OF CANCER Public/Granted day:2016-11-03
Information query
