Invention Grant
- Patent Title: Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
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Application No.: US16443250Application Date: 2019-06-17
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Publication No.: US10793836B2Publication Date: 2020-10-06
- Inventor: Oscar Alvizo , Melissa Ann Mayo , Jeffrey C. Moore
- Applicant: Codexis, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N9/06
- IPC: C12N9/06 ; C12N1/21 ; C12N15/53 ; C12P13/00 ; C07K14/195
Abstract:
The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Public/Granted literature
- US20190300865A1 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS Public/Granted day:2019-10-03
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