Invention Grant
- Patent Title: Treatment of sodium channel, voltage-gated, alpha subunit (SCNA) related diseases by inhibition of natural antisense transcript to SCNA
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Application No.: US15689713Application Date: 2017-08-29
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Publication No.: US10793857B2Publication Date: 2020-10-06
- Inventor: Joseph Collard , Olga Khorkova Sherman , Belinda De Leon , Carlos Coito , Jane H. Hsiao
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61K31/7088 ; C12Q1/6813
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sodium channel, voltage-gated, alpha subunit (SCNA), in particular, by targeting natural antisense polynucleotides of Sodium channel, voltage-gated, alpha subunit (SCNA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SCNA.
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