• Patent Title: Retro- and lenti-HBV hybrid vectors and constructs
  • Application No.: US16474661
    Application Date: 2017-12-28
  • Publication No.: US10793876B2
    Publication Date: 2020-10-06
  • Inventor: Yuntao Wu
  • Applicant: VIRONGY L.L.C.
  • Applicant Address: US VA Manassas
  • Assignee: VIRONGY L.L.C.
  • Current Assignee: VIRONGY L.L.C.
  • Current Assignee Address: US VA Manassas
  • Agency: Pilloff Passino & Cosenza LLP
  • Agent Sean A. Passino; Rachel K. Pilloff
  • International Application: PCT/US2017/068766 WO 20171228
  • International Announcement: WO2018/126042 WO 20180705
  • Main IPC: C12N15/86
  • IPC: C12N15/86 C12N7/00
Retro- and lenti-HBV hybrid vectors and constructs
Abstract:
The present disclosure relates to the design of a retro- or lenti-viral HBV (hepatitis B virus) hybrid vector for delivery of HBV genomes into cells such as liver cells. Provided herein are design, methodology, compositions, and the like for such vectors for delivering HBV genes or genomes into cells for anti-HBV drug screening, HBV research, or test of anti-HBV therapeutics.
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