Invention Grant
- Patent Title: Compositions and methods for making noscapine and synthesis intermediates thereof
-
Application No.: US14912263Application Date: 2014-08-15
-
Publication No.: US10793885B2Publication Date: 2020-10-06
- Inventor: Peter James Facchini , Xue Chen , Thi Thu Thuy Dang
- Applicant: Willow BioSciences Inc.
- Applicant Address: CA Calgary, Alberta
- Assignee: Willow BioSciences Inc.
- Current Assignee: Willow BioSciences Inc.
- Current Assignee Address: CA Calgary, Alberta
- Agency: Bereskin & Parr LLP/S.E.N.C.R.L., s.r.l.
- Agent Micheline Gravelle
- International Application: PCT/CA2014/050782 WO 20140815
- International Announcement: WO2015/021561 WO 20150219
- Main IPC: C12P17/18
- IPC: C12P17/18 ; C07D491/056
Abstract:
Methods for the manufacture of the therapeutic chemical compound noscapine and noscapine synthesis intermediates comprising contacting a noscapine pathway precursor selected from a first canadine derivative, a first papaveroxine derivative and narcotine hemiacetal with at least one of the enzymes selected from the group CYP82Y1, CYP82X1, AT1, CYP82X2, OMT, CXE1 and NOS.
Public/Granted literature
- US20160201101A1 COMPOSITIONS AND METHODS FOR MAKING NOSCAPINE AND SYNTHESIS INTERMEDIATES THEREOF Public/Granted day:2016-07-14
Information query
