Invention Grant
- Patent Title: Methods for predicting the survival time of patients with decompensated alcoholic cirrhosis
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Application No.: US15775092Application Date: 2016-11-09
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Publication No.: US10793909B2Publication Date: 2020-10-06
- Inventor: Richard Moreau , Emmanuel Weiss , Pierre-Emmanuel Rautou
- Applicant: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , UNIVERSITE PARIS DESCARTES , ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP) , UNIVERSITE PARIS DIDEROT—PARIS 7
- Applicant Address: FR Paris FR Paris FR Paris FR Paris
- Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),UNIVERSITE PARIS DESCARTES,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS (APHP),UNIVERSITE PARIS DIDEROT—PARIS 7
- Current Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),UNIVERSITE PARIS DESCARTES,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS (APHP),UNIVERSITE PARIS DIDEROT—PARIS 7
- Current Assignee Address: FR Paris FR Paris FR Paris FR Paris
- Agency: W&C IP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2b2d5a6d
- International Application: PCT/EP2016/077129 WO 20161109
- International Announcement: WO2017/081073 WO 20170518
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883
Abstract:
The present invention relates to methods for predicting the survival time of patients with decompensated alcoholic cirrhosis. In particular, the present invention relates to a method for predicting the survival time of a patient with decompensated alcoholic cirrhosis comprising i) determining the expression level of OAS2 or MX2 in a sample of peripheral blood mononuclear cells obtained from the patient, ii) comparing the level determined at step i) with a predetermined reference value and iii) and concluding that the patient will have a short survival time when the level determined at step i) is higher than its predetermined reference value or concluding that the patient will have a long survival time when the level determined at step i) is lower than the predetermined reference value.
Public/Granted literature
- US20180320232A1 METHODS FOR PREDICTING THE SURVIVAL TIME OF PATIENTS WITH DECOMPENSATED ALCOHOLIC CIRRHOSIS Public/Granted day:2018-11-08
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