In some examples, a system including one or more processors may receive sensor data from one or more sensors indicating one or more engine parameters of an engine including a combustion chamber. Based on the sensor data, the system may determine a homogeneity index indicative of a homogeneity of an air-fuel mixture within the combustion chamber. Furthermore, the system may determine an estimated amount of NOx in the exhaust gas based at least in part on the homogeneity index. In addition, based at least partially on the estimated amount of NOx in the exhaust gas, the system may send an instruction to control an engine component.