A framework for selective image reconstruction. In accordance with one aspect, the framework receives at least one first image that is reconstructed based on at least one first reconstruction attribute. At least one region of interest may then be identified in the at least one first image. The framework may selectively reconstruct at least one second image of the region of interest based on at least one second reconstruction attribute, wherein the second reconstruction attribute is different from the first reconstruction attribute. Results may then be generated based on the at least one second image.