The invention provides a display control circuit, method and panel display device. The display control circuit includes: a current source, a first capacitor, a discharge circuit, a subtractor, and an initial reference voltage generating module; the current source coupled to first end of the first capacitor to generate a charging voltage changing with time, and second end of the first capacitor grounded; the discharge circuit connected to first end of the first capacitor to clear the charging voltage at beginning of each frame; a negative input end of the subtractor inputting the charging voltage, a positive input end of the subtractor connected to output end of the initial reference voltage generating module, and the subtractor outputting an adjusted reference voltage required for different regions of display panel; the initial reference voltage generating module outputting a fixed initial reference voltage; the adjusted reference voltage used for generating a gamma voltage.