A handsfree voice system has a microphone mounted in a fixed location in a passenger cabin. An audio signal from the microphone can be used by a voice recognition system to detect spoken commands of a driver or can be used by a cellular telephone transceiver to transmit sounds for a spoken conversation over a phone call. A pair of speakers is mounted at a periphery of the microphone. A plurality of noise sensors are configured to characterize intrusive noises into the cabin. An active noise cancellation controller is responsive to the noise sensors for generating anti-noise to be output by the speakers establishing a quiet zone centered on the microphone.