A display substrate, a display panel, and a display device. The display substrate includes multiple pixel units arranged in an array manner. At least one of pixel unit includes a first electrode. Each first electrode includes a first electrode body, a first electrostriction layer connected to the first electrode body, and a first drive electrode electrically connected to the first electrostriction layer. The first electrostriction layer is configured to be expanded and shrunk with an electrical signal of the first drive electrode and to drive the first electrode body to be expanded and shrunk.