Systems and methods are disclosed for personalized communications using semantic memory. In one implementation, a first communication is received from a user and processed to identify a first content element within the communication. The first content element is associated with a second content element within a content repository. A second communication that includes the first content element is received from the user. Based on an association between the first content element and the second content element within the content repository, a third communication that includes the second content element is generated and provided to the user in response to the second communication.