Invention Grant
![4-(aryl)-N-(3-alkoxyfuro[2,3-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative and antiproliferative effect thereof](/docs/US/2020-10-13/US10800788B2/abs.jpg.600x600.jpg)
- Patent Title: 4-(aryl)-N-(3-alkoxyfuro[2,3-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative and antiproliferative effect thereof
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Application No.: US16308028Application Date: 2017-06-09
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Publication No.: US10800788B2Publication Date: 2020-10-13
- Inventor: Young-Dae Gong , Soo-Youl Kim , Eun Sil Lee , Tae-Sung Koo , Nam-Sook Kang , Na Yeon Kim
- Applicant: Dongguk University Industry-Academic Cooperation Foundation
- Applicant Address: KR Seoul
- Assignee: LSK NRDO CO., LTD.
- Current Assignee: LSK NRDO CO., LTD.
- Current Assignee Address: KR Seoul
- Agency: Chalker Flores, LLP
- Agent Edwin S. Flores; Daniel J. Chalker
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6ea56ebe com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@f98dd33
- International Application: PCT/KR2017/006004 WO 20170609
- International Announcement: WO2017/213452 WO 20171214
- Main IPC: C07D491/048
- IPC: C07D491/048
![4-(aryl)-N-(3-alkoxyfuro[2,3-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative and antiproliferative effect thereof](/abs-image/US/2020/10/13/US10800788B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a novel 4-(aryl)-N-(3-alkoxyfuro[2,3-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative compound useful in the prevention or treatment of cancer; a preparation method thereof; and a pharmaceutical composition comprising the same. The novel 4-(aryl)-N-(3-alkoxyfuro[2,3-b]pyrazin-2-yl)-piperazine-1-carboxamide derivative compound of the present invention can effectively inhibit the growth of proliferating cells, and thus can be useful in the prevention or treatment of cancer.
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