Methods and systems for installing tires to corresponding wheels are disclosed. An example method includes measuring non-uniformity of a first assembled tire and wheel at three or more different relative rotational positions to determine corresponding measurements of non-uniformity according to a predetermined metric, and determining that each of the measurements are above a predetermined non-uniformity limit. A rotationally relative installation position for the tire on the wheel may be determined using at least these measurements, with the position of the tire relative to the wheel in the rotationally relative installation position being different from each of the first, second, and third relative rotational positions. In examples where at least a second tire/wheel combination is measured below the non-uniformity threshold, installation of the second tire/wheel may conclude at the position where the assembled tire/wheel is measured below the non-uniformity threshold.