Invention Grant
- Patent Title: Compositions and methods for the treatment of a beta-catenin-associated disease or disorder
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Application No.: US16084852Application Date: 2017-03-15
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Publication No.: US10821112B2Publication Date: 2020-11-03
- Inventor: Marc Abrams , Shanthi Ganesh
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Lexington
- Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee Address: US MA Lexington
- Agency: MH2 Technology Law Group, LLP
- Agent Byron V. Olsen
- International Application: PCT/US2017/022510 WO 20170315
- International Announcement: WO2017/160983 WO 20170921
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/7088 ; A61K9/00 ; A61P35/00 ; A61K9/51 ; C12N15/113
Abstract:
Disclosed herein are methods for the treatment of cancer, comprising administering to a subject a β-catenin nucleic acid inhibitor molecule and a therapeutically effective amount of an MEK inhibitor or a c-Myc nucleic acid inhibitor molecule. Also disclosed herein is a pharmaceutical composition comprising a therapeutically effective amount of a β-catenin nucleic acid inhibitor molecule; a therapeutically effective amount of an MEK inhibitor or a c-Myc nucleic acid inhibitor molecule and at least one pharmaceutical carrier.
Public/Granted literature
- US20190070180A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF A BETA-CATENIN-ASSOCIATED DISEASE OR DISORDER Public/Granted day:2019-03-07
Information query
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