The present invention relates to the pharmaceutical field, particularly to a composition and the use thereof. The composition serves to lower uric acid through the combination of several traditional Chinese medicines of Smilacis glabra rhizoma, Cichorii herba, Plantaginis herba and Coicis semen. On the basis of the combination of the traditional Chinese medicines described above, the addition of Alismatis rhizoma is able to improve the effect of lowering uric acid more significantly. Further, on the basis of the combination of the traditional Chinese medicines described above, the addition of tuna was able to improve the effect of lowering uric acid more significantly. A comprehensive analysis of the experimental results described above indicates that the compositions provided in the present invention have a significant effect of lowering uric acid.