According to principles of the present inventive concepts, an HVAC fluid conditioning system comprises an inlet port configured to receive HVAC fluid from an HVAC condensation line. A conditioning system treats the HVAC fluid with a chemical or other treatment process to prevent the growth of harmful pollutants within the HVAC condensation line. The treated HVAC fluid is then released from the conditioning system through an outlet port thereof and back into the HVAC condensation line. A trap system can be provided to trap harmful gases created during the HVAC fluid treatment process.