Invention Grant
- Patent Title: Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
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Application No.: US16519552Application Date: 2019-07-23
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Publication No.: US10822326B2Publication Date: 2020-11-03
- Inventor: Brian Metcalf , Chihyuan Chuang
- Applicant: Global Blood Therapeutics, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Global Blood Therapeutics, Inc.
- Current Assignee: Global Blood Therapeutics, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Sheppard Mullin Richter & Hampton LLP
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D213/65 ; C07D213/68 ; C07D213/69 ; C07D213/80 ; C07D401/14 ; C07D405/14 ; C07D413/12 ; C07D471/04 ; C07D487/04
Abstract:
Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
Information query
