Invention Grant
- Patent Title: Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders
-
Application No.: US16351203Application Date: 2019-03-12
-
Publication No.: US10822352B2Publication Date: 2020-11-03
- Inventor: Jason Allan Wiles , Avinash S. Phadke , Milind Deshpande , Atul Agarwal , Dawei Chen , Venkat Rao Gadhachanda , Akihiro Hashimoto , Godwin Pais , Qiuping Wang , Xiangzhu Wang
- Applicant: Achillion Pharmaceuticals, Inc.
- Applicant Address: US CT New Haven
- Assignee: Achillion Pharmaceuticals, Inc.
- Current Assignee: Achillion Pharmaceuticals, Inc.
- Current Assignee Address: US CT New Haven
- Agency: Clark & Elbing LLP
- Main IPC: A61P25/00
- IPC: A61P25/00 ; A61P25/02 ; A61P19/02 ; A61P9/00 ; A61P11/00 ; A61P13/02 ; A61P13/00 ; A61P21/00 ; A61P1/16 ; A61P17/00 ; A61P27/02 ; A61P27/00 ; A61P43/00 ; A61P3/06 ; A61P29/00 ; A61P9/10 ; C07D487/04 ; C07D513/04 ; C07D409/14 ; C07D493/04 ; C07D413/14 ; C07D401/14 ; C07D495/04 ; C07D471/04 ; C07D417/14 ; C07D403/14 ; C07D403/06 ; C07D405/14
Abstract:
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an aryl, heteroaryl or heterocycle (R32) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.
Public/Granted literature
- US20190211033A1 ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS Public/Granted day:2019-07-11
Information query
