Invention Grant
- Patent Title: Benzyl compound
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Application No.: US15755705Application Date: 2016-08-25
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Publication No.: US10822357B2Publication Date: 2020-11-03
- Inventor: Shinya Yano , Yuki Wakasugi , Yosuke Iwanaga
- Applicant: SEKISUI MEDICAL CO., LTD.
- Applicant Address: JP Chuo-ku
- Assignee: SEKISUI MEDICAL CO., LTD.
- Current Assignee: SEKISUI MEDICAL CO., LTD.
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@35ccd081 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@b4fb8cd com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@659d7433
- International Application: PCT/JP2016/074888 WO 20160825
- International Announcement: WO2017/038650 WO 20170309
- Main IPC: C07F7/18
- IPC: C07F7/18 ; C07B51/00 ; C07K1/06

Abstract:
The purpose of the present invention is to provide a protecting group which improves the solubility of a compound having a functional group protected with the protecting group in an organic solvent and which is easily separated and purified after a reaction with avoiding solidification or insolubilization. Provided is a benzyl compound represented by Formula (1) where X1 represents —CH2OR14 (where R14 represents a hydrogen atom, a halogenocarbonyl group, or an active ester-type protecting group), —CH2NHR15 (where R15 represents a hydrogen atom, a linear or branched alkyl group having 1 to 6 carbon atoms, or an aralkyl group), a halogenomethyl group, a methyl azide group, a formyl group, or an oxime; and at least one of R1, R2, R3, R4, and R5 is a group represented by Formula (2), and the remainders each represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms, or an alkoxy group having 1 to 4 carbon atoms, where R6 represents a linear or branched alkylene group having 1 to 16 carbon atoms; X2 represents O or CONR16 (where R16 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms); and A represents a group represented by Formula (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), or (13).
Public/Granted literature
- US20190023726A1 BENZYL COMPOUND Public/Granted day:2019-01-24
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