Invention Grant
- Patent Title: Measurement of analytes with membrane channel molecules, and bilayer arrays
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Application No.: US15326109Application Date: 2015-07-09
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Publication No.: US10822655B2Publication Date: 2020-11-03
- Inventor: Mark Wallace , Hagan Bayley , Shuo Huang , Oliver Kieran Castell , Mercedes Romero-Ruiz
- Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
- Applicant Address: GB Oxford
- Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee Address: GB Oxford
- Agency: Nixon Peabody, LLP
- Agent Mark J. FitzGerald
- International Application: PCT/GB2015/051996 WO 20150709
- International Announcement: WO2016/009180 WO 20160121
- Main IPC: C12Q1/6874
- IPC: C12Q1/6874 ; G01N33/487 ; C12Q1/6869 ; G01N21/77
Abstract:
The invention relates to a method for detection of analyte interaction with a channel molecule held in a membrane, comprising the optical detection of a modification in the flux of a signal molecule as it passes through the channel molecule by the action of a membrane potential, wherein the modification in the flux is caused by at least partial blockage of the channel molecule by the analyte. The invention further relates to bilayer arrays, components, methods of manufacture and use.
Public/Granted literature
- US20170226578A1 MEASUREMENT OF ANALYTES WITH MEMBRANE CHANNEL MOLECULES, AND BILAYER ARRAYS Public/Granted day:2017-08-10
Information query
