A screw with an asymmetrical thread for securing wooden members together is disclosed. The screw includes a shaft with a head at one end and a tip at the other end. A continuous asymmetrical thread extends along the shaft. The asymmetrical thread has a front surface facing the tip and a rear surface facing the head, the front and rear surfaces each having an angle relative to a plane normal to the shaft. The asymmetrical thread has a first section and a second section. The portion of asymmetrical thread in the first section has front and rear surfaces of first angles with respect to the plane normal to the shaft. The portion of asymmetrical thread in the second section has front and rear surfaces of second angles different than the first angles. The asymmetrical thread includes a transition portion between the first and second sections. The transition portion is positioned along the shaft such that the transition portion is located proximate the interface of the wooden members when the screw secures the wooden frame members together and the head of the screw engages the first of the wooden members.