Technologies for dynamically managing the reliability of disaggregated resources in a managed node include a resource manager server. The resource manager server includes communication circuit to receive resource data from a set of disaggregated resources that indicates reliability of each disaggregated resource of the set of disaggregated resources and a node request to compose a managed node. The resource manager server further includes a compute engine to determine node parameters from the node request indicative of a target reliability of one or more disaggregated resources of the set of disaggregated resources to be included in the managed node, compose a managed node from the set of disaggregated resources that satisfies the node parameters by configuring the compute sled to utilize the disaggregated resources of the managed node for the execution of a workload, and monitor the disaggregated resources of the managed node for a failure.