The present disclosure is directed towards systems and methods for managing application delivery in a network. A device intermediary to a client and one or more servers that provide a plurality of applications, receives a request from the client to access a first application of the plurality of applications. The device holds the request and retrieves, while holding the request, configuration information for an instance of the first application from a configuration repository. The device configures a virtual internet protocol (“VIP”) server using the configuration information for the instance of the first application. The device processes the request via the VIP server.