A lock-out, tag-out system for use with an appliance having a door includes a lock for controlling opening of the door. The lock has a locked state and an unlocked state. A controller is communicatively coupled to the lock. An automatic identification and data capture system includes a tag and a reader. The reader is communicatively coupled to the controller. When the reader receives a signal from the tag indicating the presence of the tag within an opening envelope, the reader communicates with the controller to transmit a signal to the lock to change the state of the lock from the locked state to the unlocked state. The tag is located on or in the personal protective equipment item. The system may include a second tag on the appliance, the signal of which is attenuated by a user's body and compared to the signal from the first tag to determine whether protective equipment is worn.